SYK Antikörper (pTyr525, pTyr526)
Kurzübersicht für SYK Antikörper (pTyr525, pTyr526) (ABIN7676197)
Target
Alle SYK Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pTyr525, pTyr526
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Kreuzreaktivität (Details)
- Expected species reactivity: Mouse,Rat,Pig
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Aufreinigung
- Antigen affinity purified
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Immunogen
- This phospho-Syk antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pY525/526 of human Syk.
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Isotyp
- Ig Fraction
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anti-Spleen tyrosine Kinase (SYK) (AA 5-360) antibody
SYK Reaktivität: Human, Maus, Ratte WB, IP, IHC (p), ICC Wirt: Maus Monoclonal SYK-01 unconjugated
anti-Spleen tyrosine Kinase (SYK) (Internal Region) antibodySYK Reaktivität: Human, Maus, Ratte WB, IF, IP, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Spleen tyrosine Kinase (SYK) (pTyr525) antibodySYK Reaktivität: Human, Maus, Ratte, Affe WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Spleen tyrosine Kinase (SYK) (pTyr348) antibodySYK Reaktivität: Human, Maus, Ratte, Affe WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Spleen tyrosine Kinase (SYK) (pTyr323) antibodySYK Reaktivität: Human, Maus, Ratte, Affe WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Spleen tyrosine Kinase (SYK) (AA 217-356) antibodySYK Reaktivität: Human ELISA, ICC, FACS Wirt: Maus Monoclonal 2G11E6 unconjugated
anti-Spleen tyrosine Kinase (SYK) (AA 217-356) antibodySYK Reaktivität: Human WB, ELISA, FACS Wirt: Maus Monoclonal 3D1G10 unconjugated
anti-Spleen tyrosine Kinase (SYK) (AA 387-417), (C-Term) antibodySYK Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB03097 unconjugated
anti-Spleen tyrosine Kinase (SYK) (AA 374-635) antibodySYK Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Spleen tyrosine Kinase (SYK) (pTyr525), (pTyr526) antibodySYK Reaktivität: Human, Maus WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Titration of the phospho-Syk antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the phospho-Syk antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- SYK (Spleen tyrosine Kinase (SYK))
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Andere Bezeichnung
- SYK
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Hintergrund
- Syk is a positive effector of BCR-stimulated responses. This protein couples the B-cell antigen receptor (BCR) to the mobilization of calcium ion either through a phosphoinositide 3-kinase-dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C-gamma-dependent pathway, when phosphorylated on Tyr-342 and Tyr-346. Thus the differential phosphorylation of Syk can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ion.
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UniProt
- P43405
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Pathways
- Fc-epsilon Rezeptor Signalübertragung, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling
Target
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